Effects of long-term administration of royal jelly on pituitary weight and gene expression in middle-aged female rats.

نویسندگان

  • Yukio Narita
  • Shozo Ohta
  • Kazu-Michi Suzuki
  • Tomoko Nemoto
  • Keiko Abe
  • Satoshi Mishima
چکیده

To determine the effects of ingested royal jelly (RJ) on the pituitary in middle-aged female rats, we performed a long-term RJ administration test. Several animals showed age-related increases in pituitary weight, and RJ administration compensated for the increase. RJ tended to down-regulate prolactin mRNA and up-regulated thyroid-stimulating hormone beta mRNA in the pituitary. This suggests that RJ compensates for age-associated decline in pituitary functions.

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عنوان ژورنال:
  • Bioscience, biotechnology, and biochemistry

دوره 73 2  شماره 

صفحات  -

تاریخ انتشار 2009